The H4 Minor Histocompatibility Antigen Is Caused by a Combination of Genetically Determined and Posttranslational Modifications
نویسندگان
چکیده
منابع مشابه
The H4b minor histocompatibility antigen is caused by a combination of genetically determined and posttranslational modifications.
Minor histocompatibility (H) Ag disparities result in graft-vs-host disease and chronic solid allograft rejection in MHC-identical donor-recipient combinations. Minor H Ags are self protein-derived peptides presented by MHC class I molecules. Most arise as a consequence of allelic variation in the bound peptide (p) that results in TCR recognizing the p/MHC as foreign. We used a combinational pe...
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